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About Nizatidine API

Product

  • Therapeutic CategoryGastro-Intestinal - GI

  • CAS Number

    76963-41-2

  • API Technology

    Synthetic

  • Dose Form

    Oral Solid/Capsules

  • Dr Reddy's Development Status

    Available

  • Available Regulatory Filing

    USDMF, CEP Submitted, Japan DMF, Korea DMF

Mechanism of Action

Nizatidine competes with histamine for binding at the H2-receptors on the gastric basolateral membrane of parietal cells. Competitive inhibition results in reduction of basal and nocturnal gastric acid secretions. The drug also decreases the gastric acid response to stimuli such as food, caffeine, insulin, betazole, or pentagastrin.

Indication

For the treatment of acid-reflux disorders (GERD), peptic ulcer disease, active benign gastric ulcer, and active duodenal ulcer.

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Related Resources

Famotidine and Nizatidine APIs: NDMA controlled, customized particle distribution, supply chain security

Famotidine and Nizatidine APIs: NDMA controlled, customized particle distribution, supply chain security

For more than two decades, Dr. Reddy's has been recognized as one of the largest manufacturers of H2 receptor antagonist APIs such as Famotidine and Nizatidine. Our Tidine APIs are used by formulation companies across Europe, US, Japan, Middle-East and Asia Pacific.Manufactured and controlled in accordance with the international guidelines on nitrosamine impurities, these APIs are available in customized particle size distribution to ideally meet your formulation needs.Read the tech sheet on Famotidine and Nizatidine by filling the contact form below.You can also explore our Tidine API offerings by clicking on the links below:Famotidine: https://api.drreddys.com/product/famotidineNizatidine: https://api.drreddys.com/product/nizatidine
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Disclaimer: Products under patent(s) are offered only for R&D purposes U/S 107A of the Patent Act (Bolar Exemption) and not for commercial sale.