About Lomustine API
Therapeutic CategoryAnti-Cancer/ Oncology
CAS Number
13010-47-4
API Technology
High Potent
Dose Form
Oral Solid/Capsules
Dr Reddy's Development Status
Available
Available Regulatory Filing
USDMF, CEP Submitted, Russia DMF, China DMF
Mechanism of Action
Lomustine alkylates DNA and RNA. As with other nitrosoureas, it may also inhibit several key enzymatic processes by carbamoylation of amino acids in proteins.
Indication
Gleostine is an alkylating drug indicated for the treatment of patients with:
- Brain tumors, primary and metastatic, following appropriate surgical and/or radiotherapeutic procedures.
- Hodgkin’s lymphoma in combination with other chemotherapies, following disease progression with initial chemotherapy.
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