About Palbociclib API
Therapeutic Category抗癌 / 肿瘤学
CAS Number
571190-30-2
API Technology
Synthetic
Dose Form
Capsule/ Tablet, Oral Solids
Dr Reddy's Development Status
Available
Available Regulatory Filing
Brazil DMF, USDMF, Singapore DMF
Mechanism of Action
It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6.
Indication
IBRANCE is a kinase inhibitor indicated for the treatment of hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced or metastatic breast cancer in combination with:
- An aromatase inhibitor as initial endocrine based therapy in postmenopausal women; or
- Fulvestrant in women with disease progression following endocrine therapy.
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